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Basically an anti-depressant from the Selective Serotonin Reuptake Inhibitors drug group, the generic name of Paxil is Paroxetine. By impacting the chemical in the brains of people suffering from Anxiety and Depression, Paxil treats Premenstural Dysphoric Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder and Anxiety disorders among many. The brand names of Paxil are Pexeva, Paxil CR and Paxil

Product Description

Considered as the most potent among the specific selective Serotonin Reuptake Inhibitors (SSRIs) , Paxil is made up of 5-hydroxytryptamine, 5-HT.

Working Mechanism

The nerves in the Brain produce neurotransmitters that get attached to the nearby nerves enabling a communication system. Serotonin one such neurotransmitter travels between the nerves attaching themselves to the receptors on the nearby nerves. This process is called as Re-uptake. Increasing the activity of Serotonin in the brain, Paxil affects the neurotransmitters, which in turn impacts the communication that happens between the nerves in the Brain. The Serotonin transporter gets antagonized during this entire process. Antiobsessional, Antidepressant and Antipanic are reactions linked to the serotonergic activities in the Central Neuro System. While this activity increases its Neuro transmission, through a negative feedback mechanism, it tends to reduce the turnover of the Neuro Transmitter thus having control over Anxieties and Depression symptoms.

Dosage Patterns

Paxil is available in many forms depending on the dosage to be administered. The usual forms are Tablet (extended release), Suspension, Tablet and Capsule.

1.      Paxil is available in four dosages 10 mg, 20 mg, 30 mg, and 40 mg.

2.      The typical consumption is two tablet daily one in the morning and one in the evening and the dosage of the same differs from patient to patient and as advised by the Doctor

3.      For initial stages 20 Mg is the usually prescribed dosage.

4.      For patients suffering from Panic Disorder and Obsessive-Compulsive Disorder, the usual dosage recommended is a 40 mg

5.      20 Mg to 50 Mg is recommended for people suffering from Major Depressive Disorder

6.      For people suffering from Social Anxiety Disorder the dosage recommended is 20 Mg to 60 Mg

7.      For those with Post Traumatic Stress Disorder the dosage is 20 Mg per day

8.      Ensure that the dosage does not exceed 60 Mg per day to avoid serious side effects

9.      Paxil taken with food helps alleviate chances from the stomach getting upset

10.  Paxil must be taken only as per the Doctor’s advice and must not be taken beyond the recommended period of time and any extension without the Doctor’s advice may be fatal

11.  The Extended release table must be swallowed as a whole and should not be broken or crushed

12.  Using Paxil suddenly may give rise to withdrawal symptoms that are unpleasant or unmanageable

13.  If a dosage is missed out, take the same as soon as you remember or skip it if it is time for the next dose. Do not take two doses together as it may be fatal


1.      Paxil must be stored in a room temperature that is between 77 degrees Fahrenheit or 25 degrees Celsius.

2.      It must be stored away from moisture and light

3.      It must not be flushed in the toilet or drain but properly discarded on expiry or when no more required.


1.      Do not use Paxil if you are taking Pimozide or Thioridazine or if you are under treatment where Methylene Blue Injection is used.

2.      Avoid using Paxil within 2 weeks of using MAO inhibitors such as Linezolid, Phenelzine, Methylene Blue Injection, Tranylcypromine, Rasagiline, Selegiline or Isocarboxazid

3.      Do not use Paxil if you have allergic symptoms to Thioridazine, Pimozide and Paroxetine

4.      Patients suffering from a Blood clotting or Bleeding disorder, Heart disease, High Blood Pressure, history of Stroke; Kidney or Liver disease, Narrow-angle Glaucoma, Epilepsy or Seizures, history of Suicidal Thoughts or Drug Abuse, Bipolar Disorder and low levels of Sodium in their blood must ensure to keep the Doctor informed about the same to avoid any fatal results

5.      Paxil must not be taken by children and must be administered only for adults above 18 years of age

6.      Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

7.      Do not breast feed while using Paxil. Rather do not take Paxil while breast feeding

8.      The side effects of Paxil is violent when Alcohol is consumed while under Paxil medication

9.      While being administered on Paxil, avoid taking Non-steroidal anti-inflammatory drugs like Aspirin,  Meloxicam, Celecoxib (Celebrex), Naproxen (Aleve), Diclofenac, Indomethacin, Ibuprofen (Motrin, Advil) which are usually advocated for Swelling, Fever, Arthritis and pain. Consuming Paxil along with these medicines may impair the reactions and thinking and so avoid doing anything that needs your complete attention like driving etc.

Side Effects

Some people experience mild side effects when Paxil is administered. However side effects are more and worse when Paxil is taken without the Medical practitioner’s advice. 

1.       Insomnia (Sleep problems)

2.       Change in Vision

3.       Yawning, Dried Mouth

4.       Shaking, Anxiety & Sweating

5.       Constipation and Loss of Appetite

6.       Difficulty getting Orgasm, low Sex drive and Impotence

7.       Dizziness, Drowsiness and feeling weak

8.       Skin Hives or rashes

9.       Swelling of Face, Throat, Tongue and Lips

10.    Panic Attacks

11.    Behavior or Mood changes

12.    Feeling Hostile, Aggressive, Restless, Irritable, Impulsive and agitated

13.    Hyperactive physically or Mentally

14.    Getting Suicidal thoughts or urge to cause harm to self

15.     Unusual behavior to take risks

16.    Being more talkative than usual

17.    Bruise or swelling or tenderness or pain in bones

18.    Sudden Seeing halos around lights, Tunnel Vision or Blurred vision

19.    Weight loss or gain

20.    Unusual bleeding from Rectum, Vagina, Mouth or Nose

21.    Fast or uneven heart beats

22.    Rigid Muscles

23.    Nausea vomiting

24.    Loss of co-ordination and feeling unsteady

25.    Fast heart beats and over impulsive reflexes

26.    Sweating, Confusion, Tremors and fainting

27.    Skin pain, blistering and peeling

28.    Sore throat

29.    Chest Congestion and pain

30.    Chills and cold sweats

31.    Sour stomach or Acidity

32.    Frequent Belching

33.    Enlarged pupils

34.    Difficulty with speaking